
The enhanced Tirzepatide formulation with Glycine for injection site comfort and Methylcobalamin B12 for metabolic support. Compounded under 503A standards and shipped to clinics in 42 states.
This combination formulation pairs Tirzepatide (a dual GIP/GLP-1 receptor agonist) with Glycine and Methylcobalamin B12 in a single injectable vial. Glycine is included to improve injection site tolerance, which many patients report as a concern with GLP-1 and GIP agonist therapies. B12 provides metabolic support that complements the weight management protocol. This formulation has become one of the most popular GLP-1 compounds ordered through Promise Pharmacy.
Many weight loss clinics have shifted from standalone Tirzepatide to the Glycine + B12 combination because it addresses two common patient concerns in one vial: injection site discomfort and metabolic nutrient support during caloric restriction. Prescribers report that patients on the combination formulation are more compliant with their injection schedule and experience fewer complaints about injection site reactions. The single-vial design also simplifies clinic inventory and reduces per-patient preparation time.
Single-Vial Simplicity. One injection delivers the dual agonist plus supportive compounds. Less inventory, less prep, better compliance.High Patient Satisfaction. Clinics report fewer injection site complaints and stronger adherence with the Glycine-enhanced formula.In-Stock Availability. This is one of our highest-volume compounds. Consistent supply across all concentrations.Direct Pricing. No broker fees on any GLP-1 formulation, including combination compounds.
Glycine acts as a buffering amino acid that can improve injection site tolerance. Many clinics report reduced patient complaints about injection site reactions when using the Glycine-enhanced formulation.
The combination is priced competitively. Contact your Promise account manager for current pricing across all Tirzepatide formulations.
A single access point for a wide range of 503A formulary products, catering to the requirements of any medical clinic, med spa, or telehealth provider.


At Promise Pharmacy, our dedicated team of hormone health specialists is led by Amy Patel, a seasoned expert in sterile compounding with more than 25 years of experience.