Compounded Ophthalmic Formulations and Combo Drops for Ophthalmology Practices

600 Clinics Served
503A Compounding
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Compounded wellness medications prepared by Promise Pharmacy

Ophthalmology is one of the most exacting disciplines in medicine, and the standards for compounded ophthalmic preparations reflect that. Sterile formulation, precise concentration, single-dose accuracy, and reliable packaging are not preferences in this category. They are clinical requirements.

Promise Pharmacy has extensive experience compounding sterile ophthalmic preparations for ophthalmology offices, LASIK centers, and ambulatory surgical centers. Our flagship ophthalmic product line, the Combo Drops series, simplifies the pre- and post-operative medication regimen for patients undergoing cataract and refractive surgery while significantly reducing out-of-pocket costs.

The Problem With Standard Post-Surgical Eye Drop Protocols

The standard of care following cataract surgery and LASIK typically involves multiple eye drop medications prescribed separately. Patients are often managing three or four different bottles, each with its own dosing schedule, refill timeline, and co-pay. The result is a logistical challenge that drives non-adherence and creates unnecessary expense.

Commercial eye drop regimens following cataract surgery can cost patients hundreds of dollars out of pocket, even with insurance. Prior authorization requirements, formulary restrictions, and co-pay tiers add complexity and delay. And despite all of that, patients are still left managing multiple bottles with different dosing instructions.

Compounded Combo Drops from Promise Pharmacy address all of these problems simultaneously.

Promise Pharmacy Combo Drops for Cataract and LASIK Surgery

Our Combo Drops line combines two or three active medications into a single bottle with a single dosing schedule. This dramatically simplifies the patient experience, improves medication adherence, and reduces the total out-of-pocket cost compared to purchasing individual commercial drops.

Because Combo Drops are not billed through insurance, prior authorization requirements and formulary restrictions are entirely eliminated. The prescription goes directly from the surgeon to the pharmacy, and the patient receives a single, clearly labeled bottle with all of the medications they need in one solution.

Clinical Advantages of Combo Drops

  • Single bottle replaces three or four separate prescriptions
  • One dosing schedule improves patient compliance and reduces confusion
  • Patient cost is approximately one-third to one-half of separate commercial co-pays
  • No insurance prior authorization delays
  • Convenient USPS Priority shipping directly to the patient, eliminating in-store pickup
  • Precise drop calibration ensures the correct dose is delivered every time, eliminating the variability of manual application and shaking required with suspension-based drops

Available Combo Drop Formulations

Promise Pharmacy offers a full range of Combo Drop configurations to match the pre- and post-operative protocols used by your practice. Each formulation is sterile, accurately dosed, and dispensed in a configuration designed for patient ease of use.
Product / Formulation
Description / Available Forms
Prednisolone 1% / Gatifloxacin 0.5% / Bromfenac 0.09%
Three-drug combination in a single bottle. Combines a corticosteroid, fluoroquinolone antibiotic, and NSAID for comprehensive post-operative inflammation control and infection prophylaxis. Available in 7ml and 4ml sizes
Prednisolone 1% / Gatifloxacin 0.5% / Ketorolac 0.5%
Alternate NSAID combination using Ketorolac in place of Bromfenac for practices that prefer this formulation profile. Available in 4ml
Prednisolone 1% / Bromfenac 0.09%
Two-drug combination for patients or practices that use a standalone antibiotic separately. Pairs corticosteroid with NSAID. Available in 4ml
Prednisolone 1% / Gatifloxacin 0.5%
Two-drug combination pairing corticosteroid with fluoroquinolone antibiotic for practices incorporating separate NSAID therapy. Available in 4ml

Additional Compounded Ophthalmic Preparations

Beyond our Combo Drops line, Promise Pharmacy compounds a range of additional sterile ophthalmic preparations for ophthalmology practices and surgical centers.
Product / Formulation
Description / Available Forms
Custom Concentration Eye Drops
Commercially unavailable concentrations of standard ophthalmic medications for patients with specific dosing requirements or treatment protocols
Preservative-Free Formulations
Ophthalmic preparations without preservatives for patients with sensitivities, chronic dry eye, or high-frequency dosing regimens where preservative accumulation is a concern
Intracameral Preparations
Sterile intracameral injections for intraoperative use, prepared under rigorous aseptic processing conditions
Anti-VEGF Dilutions
Custom dilutions for intravitreal injection use prepared in certified sterile compounding environments
Antibiotic Combinations
Custom ophthalmic antibiotic formulas beyond what is commercially available for post-operative infection prevention and treatment
Steroid Combinations
Custom ophthalmic corticosteroid preparations for inflammation management in post-operative and chronic ophthalmic conditions

Sterile Compounding Standards for Ophthalmic Preparations

Ophthalmic formulations require sterile compounding conditions. All of our ophthalmic preparations are compounded in ISO-classified cleanrooms in compliance with USP 797 standards for sterile compounding. Our sterile processing protocols, environmental monitoring, and personnel training exceed the minimum regulatory requirements for 503A sterile compounding.

Every batch of Combo Drops and other ophthalmic preparations is subject to sterility testing, potency verification, and endotoxin testing where applicable. The integrity of a sterile ophthalmic preparation is not negotiable, and our quality systems reflect that.

We are LegitScript certified and 503A compliant, and our pharmacy has built a track record of clean quality records across our sterile ophthalmic product line.

Ordering Combo Drops for Your Surgical Practice

Ordering Promise Pharmacy Combo Drops for your cataract or LASIK patients is straightforward. Prescriptions can be called in, faxed, or submitted through our provider portal. We ship directly to patients via USPS Priority Mail, with shipping cost included in the product price.

For surgical centers and practices with high volumes of cataract cases, we offer streamlined ordering workflows that can accommodate your surgical schedule and patient flow. Our account team can work with your practice to establish efficient reorder processes.

To get started or to learn more about adding Promise Pharmacy Combo Drops to your surgical protocols, contact our team directly at [email protected].

Simplify Your Post-Op Eye Drop Protocol

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Meet Our Team of Compounding Experts

At Promise Pharmacy, our dedicated team of hormone health specialists is led by Amy Patel, a seasoned expert in sterile compounding with more than 25 years of experience.

Dee Patel, PharmD
CEO
Amy Patel, Rph
COO
Amar Patel
CFO
Mike Patel
CRO
Rikin Patel
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Jacki
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Matt Orban
Director of Partnerships
Honey Arias
Success Manager
Lindsay Blumeyer
Director of Partnerships
Kristina Zappia
Director of Partnerships
Raquael Flores
Director of Partnerships
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